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Università degli Studi di Modena e Reggio Emilia
Corso di laurea in infermieristica - Sede di Modena

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Thesis TitleHow to improve door-to-needle time for treatment of ischemic stroke with intravenous fibrinolytic: an experimental study
NameMistrorigo Giulia
Supervisor(s)Nichelli Paolo, Bigliardi Guido
Academic Year2019/20
Thesis typeResearch thesis

Abstract

Purpose of the study. Acute ischemic cerebrovascular disease represents an emergency that requires an in-hospital preparation and organization such to ensure a diagnostic-therapeutic approach that is as prompt as possible. In fact in the last 25 years, health professionals are claiming that "time is brain" by trying more and more to reduce the time spent from the onset of stroke to the administration of the suitable therapy. After a review of the ischemic stroke, comprehensive of epidemiologic data, risk factors, etiopathogenesis, diagnostic framework, and therapy, this elaborate subsequently reveals its experimental matrix. This elaborate represents the proposal for a new protocol for the administration of rtPA, relying on the Stroke Unit nurse and on the introduction of the "Stroke Bag". The protocol was proposed with the aim of decrease door-to-needle times of patients affected by ischemic stroke and of demonstrate the economic, relational, and welfare benefit of the purposed protocol. As a consequence, we valorized the role of the nurse as a fundamental part in this mission. Methods and materials. The purposed protocol was experimental adopted in Baggiovara's Civil and University Hospital. Door-to-needle times obtained through the adoption of the new protocol purposed, were compared with times collected from the control group, who received the same therapy following the current protocol. Results. The control group was composed by 74 subjects, which registered DTN middle time was of 56,57 minutes (± 28,22). From the experimental group, composed by 8 subjects, it was instead obtained a DTN middle time of 37,13 minutes (± 24,26). Conclusions. From the adoption of the new protocol purposed, it was obtained a reduction of 34% of the DTN middle time.